First Preliminary Round (Round of 64)
Association Sportive d'Arta "Arta/Solar 7" "Arta/SIHD" (Djibouti) 0/1 Mekawleen

Date: 28/11/2020
Scorer: Own Goal "Alex Song" 19"
Line Up: Mahmoud Aboul Seoud / Amir Abed / Farouck Kabore / Fady Nagah / Hassan El-Shamy / Ibrahim Salah / Mohamed Megally / Mohamed Essam / Ahmed El-Shimy / Ahmed Daouda / Seifeddine Jaziri  

Mekawleen 9/1 Association Sportive d'Arta "Arta/Solar 7" "Arta/SIHD" (Djibouti)

Date: 4/12/2020
Scorers: Ahmed Daouda 2", 35" / Seifeddine Jaziri 8",10" / Farouck Kabore 22" / Mohamed Essam 51" / Fady Nagah 67" / Ahmed El-Shimy 72" / Karim Moustafa 89"
Line Up: Mahmoud Aboul Seoud / Amir Abed / Farouck Kabore / Fady Nagah / Hassan El-Shamy (Ahmed Abdel Aziz 67") / Mohamed Megally / Ibrahim Salah (Karim Moustafa 57") / Ahmed El-Shimy / Mohamed Essam (Mohamed Salem 67") / Seifeddine Jaziri (Youssef Hassan 78") / Ahmed Daouda (Wassim Naghmouchi 57") 

Second Preliminary Round (Round of 32)
Mekawleen 0/0 Etoile Du Sahel "Al-Najm Al-Sahily" (Tunisia)

Date: 22/12/2020
Line Up: Hassan Shahin / Amir Abed / Farouck Kabore / Khaled El-Husseini / Hassan El-Shamy / Ibrahim Salah / Mohamed Megally / Mohamed Essam / Youssef El-Gohary (Wassim Naghmouchi 87") / Ahmed Shoukry (Luis Edward Hinestroza Córdoba 46") / Mohamed Salem (Karim Moustafa 74")  

Etoile Du Sahel "Al-Najm Al-Sahily" (Tunisia) 2/1 Mekawleen

Date: 6/1/2021
Scorer: Seifeddine Jaziri 51"
Line Up: Hassan Shahin / Amir Abed / Farouck Kabore / Mohamed Samir / Hassan El-Shamy / Wassim Naghmouchi / Mohamed Megally / Mohamed Essam / Youssef El-Gohary (Ahmed El-Shimy 79") / Luis Edward Hinestroza Córdoba / Seifeddine Jaziri (Haythem Jouini 79")